
Deciding to treat hair loss is a significant step, and making informed choices begins with understanding your options. Finasteride remains one of the most established treatments for male pattern baldness, available in both oral and topical formulations.
This guide explains how finasteride works, compares the benefits and risks of oral versus topical options, and examines the implications of the FDA’s April 2025 warning on compounded topical products. The agency issued this alert following reports of serious adverse events, including persistent sexual dysfunction and mood changes, linked to unapproved formulations.
By reviewing the evidence and understanding safety considerations, patients and clinicians can make confident, informed decisions about finasteride therapy. This guide emphasizes evidence-based care and practical strategies for evaluating treatment suitability under proper medical supervision.
How Finasteride Works In Male Pattern Hair Loss

The science behind finasteride is targeted and specific. For men experiencing male pattern hair loss, a hormone called dihydrotestosterone (DHT) is the primary culprit, causing hair follicles to shrink and eventually stop producing hair. Finasteride works by directly addressing this hormonal trigger.
By inhibiting the enzyme responsible for creating DHT, this medication helps protect your hair follicles from further damage. Recognizing this mechanism is key to appreciating how consistent drug administration can lead to halting hair loss and sometimes reversing it, though it's important to be aware of potential adverse effects.
How DHT Drives Hair Loss And How Finasteride Blocks It
In men genetically predisposed to male pattern hair loss, the hormone dihydrotestosterone (DHT) attacks hair follicles on the scalp. This hormone is converted from testosterone by an enzyme called 5-alpha-reductase. Over time, continuous exposure to DHT causes follicles to miniaturize, producing progressively thinner, shorter hairs until they cease to grow altogether.
Finasteride works by inhibiting the 5-alpha-reductase enzyme. By blocking this enzyme, it significantly reduces the amount of DHT in your scalp and bloodstream, lifting the hormonal assault on your hair follicles. This action can slow or even stop the progression of hair loss.
While effective, it is important to know the potential adverse effects. What are the main side effects of finasteride when used for hair loss? The most discussed are:
-
Sexual dysfunction, including erectile dysfunction and low libido
-
Neuropsychiatric symptoms like depression, anxiety, and "brain fog"
-
Physical symptoms such as fatigue and testicular pain
Why Consistent 5-Alpha-Reductase Inhibition Supports Regrowth
Consistency is the foundation of successful treatment with finasteride. By taking the medication daily, you ensure that the 5-alpha-reductase enzyme remains consistently inhibited. This creates a stable, low-DHT environment around your hair follicles, giving them a chance to recover from hormonal damage.
With DHT levels suppressed, the miniaturization process can halt and, in many cases, reverse. Follicles that were producing thin, weak hairs may begin to produce thicker, healthier strands again. This steady protection is what allows for visible hair growth over time.
However, this effect only lasts as long as the drug administration continues. If you stop taking oral finasteride, your body’s DHT production will return to its previous levels, and the hair loss process will resume. This is why finasteride is considered a long-term commitment for maintaining results.
What Clinical Studies Show About Hair Count And Density Improvements
Clinical studies have consistently demonstrated the effectiveness of finasteride in treating male pattern baldness. Research provides solid evidence of its ability to increase both hair count and hair density, leading to a visibly fuller head of hair for many users.
Multiple studies highlight these improvements. For example:
-
A 2022 phase III clinical trial on topical finasteride showed significant improvements in hair count and density compared to a placebo.
-
A 2018 meta-analysis concluded that topical application can produce hair regrowth comparable to oral finasteride.
-
Another meta-analysis in 2021 reported that topical finasteride achieved similar increases in hair density as the oral version.
Are there any known long-term risks of using finasteride for hair loss? Yes. While many men use it without issue, a small percentage report persistent side effects, sometimes called "post-finasteride syndrome." This can include ongoing sexual dysfunction, depression, or anxiety that continues even after stopping the medication.
How Long It Takes For Results To Become Noticeable
Patience is essential when you start using finasteride products for hair loss. Because the hair growth cycle is a slow process, you won't see changes overnight. It takes time for the medication to lower DHT levels and for your hair follicles to respond and begin producing healthier hair.
Generally, you might start noticing a decrease in hair shedding within the first three to six months of consistent drug administration. This is an early sign that the treatment is working. However, visible hair growth and increased thickness often take longer to appear.
For most men, more substantial results from oral finasteride or topical finasteride become noticeable after about a year of daily use. The full effect of the treatment is typically seen after two years. Sticking with the routine is essential to achieving and maintaining these results.
Oral Finasteride: Efficacy & Timelines

Oral finasteride, sold under the brand name Propecia, is the FDA-approved gold standard for treating male pattern hair loss. Its efficacy has been proven over decades of use and through numerous clinical trials, making it a reliable hair loss treatment for many men.
When you start this daily drug administration, it's helpful to know what to expect and when. The journey to hair growth is a marathon, not a sprint, and understanding the typical timelines can help you stay committed and track your progress effectively.
Expected Outcomes Over 3, 6, And 12 Months
When beginning treatment with oral finasteride, setting realistic expectations for hair growth is key. The results unfold gradually over several months as your body adjusts to the medication and your hair follicles begin to recover from the effects of DHT.
Here is a general timeline of expected outcomes:
-
3 Months: You may notice a significant reduction in hair shedding. This is often the first positive sign, though visible regrowth is unlikely at this stage.
-
6 Months: Some men start to see early signs of new hair growth. These hairs may be fine and thin at first, but it indicates the follicles are reactivating.
-
12 Months: This is when more noticeable improvements in hair thickness and coverage typically appear. The results should be clearly visible compared to your starting point.
Does oral finasteride have different side effects compared to topical finasteride? Yes, the risk profile differs. Because oral finasteride is absorbed systemically, it has a higher likelihood of causing systemic side effects. Topical versions are designed to minimize this absorption, which theoretically lowers the risk, but side effects are still possible.
How To Track Progress With Photos And Scalp Mapping
Tracking your progress is a great way to stay motivated during your hair loss treatment journey. Since changes happen slowly, it can be hard to notice improvements day-to-day. Taking regular photos is one of the simplest and most effective methods for progress tracking.
For best results, take pictures of your scalp from the same angles (front, top, and crown) in the same lighting every month. This creates a clear visual record of your hair growth over time, allowing you to see subtle changes that you might otherwise miss.
For a more scientific approach, some clinicians use scalp mapping. This technique involves using high-magnification imaging to measure hair density and thickness in specific areas of the scalp. While not something you can do at home, it provides precise data to complement your photos and objectively measure the effectiveness of your oral finasteride treatment.
What Happens If You Miss Doses Or Stop Early
Consistency is critical when using finasteride products. If you occasionally miss a single dose of oral finasteride, it’s not a major issue; just resume your normal schedule the next day. However, frequent missed doses will reduce the medication's effectiveness because DHT levels will start to rise again.
The biggest consequence comes from stopping treatment altogether. Finasteride only works as long as you are taking it. Once you stop the drug administration, the 5-alpha-reductase enzyme is no longer inhibited, and DHT levels in your scalp will return to their previous state.
Within a few months of stopping, the hair loss process will restart. Any hair that you maintained or regrew while on finasteride will likely be lost over the following year. It is important to view finasteride as a long-term commitment to manage hair loss, not a cure.
Combining Oral Finasteride With Topical Minoxidil For Enhanced Growth
Can I combine finasteride with minoxidil? Yes, and it's a powerful strategy many people use for enhanced hair growth. Combining these two treatments is a popular and effective approach because they tackle hair loss from two different angles, creating a synergistic effect.
Oral finasteride works internally as a DHT blocker, addressing the hormonal cause of male pattern baldness. In contrast, topical minoxidil is a growth stimulant that works by improving blood flow to the hair follicles and extending the hair's growth phase. It does not affect hormones.
Using both as a hair loss treatment can lead to better results than using either one alone. Finasteride helps stop the miniaturization process, while minoxidil actively encourages regrowth. This dual-action drug administration is often recommended by health care providers for those seeking the most robust response to treatment.
Side Effects & Monitoring

While finasteride is an effective treatment, it's also a powerful medication with potential side effects. Being aware of the possible adverse events is essential before you begin. The decision to use finasteride products should always be made with a full understanding of the risks involved.
Proper monitoring and open communication with your health care provider are your best tools for managing these risks. Regular check-ins ensure that any issues can be addressed promptly, making your treatment journey as safe as possible. We’ll now explore the common side effects and how to manage them.
Common Side Effects And How Often They Occur
When considering finasteride, it is essential to be fully informed about the potential side effects. While most men tolerate the medication well, a small percentage experience adverse effects. In clinical trials for oral finasteride, these side effects were reported in about 2-4% of users.
What are the main side effects of finasteride when used for hair loss? They can be categorized as follows:
-
Sexual Side Effects: This is the most widely discussed category and includes erectile dysfunction, decreased libido (sex drive), and testicular pain.
-
Neuropsychiatric Side Effects: Some users have reported mood changes, such as depression, anxiety, insomnia, and cognitive issues often described as "brain fog."
-
Physical Side Effects: General fatigue has also been noted in some cases.
It is important to report any new or concerning symptoms to your doctor immediately. The risk of these side effects is a key part of the conversation you should have with your provider before starting this hair loss treatment. Consistent drug administration under medical supervision is the safest path forward.
What Research Shows About Sexual Side Effects And Reversibility
Research into the sexual side effects of finasteride has produced mixed but important findings. Most clinical trials indicate that these issues are uncommon and, for the majority of men who experience them, reversible upon stopping the medication. The body typically clears the drug within about a week, at which point side effects often resolve.
What sexual side effects can occur with finasteride? The most commonly reported issues include:
-
Low libido (decreased interest in sex)
-
Erectile dysfunction (difficulty achieving or maintaining an erection)
-
Ejaculatory disorders (such as reduced volume)
However, a more serious concern is the phenomenon known as post-finasteride syndrome (PFS). This is a condition where sexual, neurological, and physical side effects persist long after a patient has stopped taking the drug. The FDA alert on topical finasteride noted that in most of the reported cases, adverse events continued after discontinuation, highlighting that reversibility is not guaranteed for everyone.
When To Pause Or Discuss Dose Adjustments With Your Clinician
If you start experiencing any side effects while taking finasteride, the first and most important step is to contact your clinician. Do not make any changes to your treatment on your own. Open and honest communication with your health care provider is essential for managing your health safely.
Your doctor can help you determine if the symptoms are related to the finasteride products or if there might be another underlying cause. They will review your experience and medical history to provide personalized guidance. Ignoring adverse effects can lead to more significant problems down the road.
Based on your symptoms, your provider might recommend several options. They may suggest pausing the treatment to see if the side effects subside, or in some cases, a dose adjustment could be considered. Ultimately, any decision to alter your treatment plan must be made in partnership with a medical professional to minimize risk.
The Importance Of Ongoing Follow-Up And Lab Checks
Treating hair loss with finasteride is a long-term commitment that requires more than just taking a pill every day. Ongoing follow-up with your health care provider is a critical part of ensuring your treatment is both effective and safe over the long run. These check-ins are not just for tracking hair growth.
Regular appointments allow your doctor to monitor for any potential adverse events and discuss how you are feeling. This is your opportunity to bring up any concerns, no matter how minor they may seem. This proactive approach helps catch and manage any issues early.
In some cases, your provider may recommend periodic lab checks to monitor your hormone levels or other health markers. This provides an extra layer of safety and ensures the medication is not negatively impacting your overall well-being. Always follow the medical advice of your clinician regarding follow-ups and testing.
2025 FDA Warning, Compounded Topical Sprays
In April 2025, the U.S. Food and Drug Administration (FDA) issued an important alert regarding finasteride. The FDA warning specifically targeted compounded topical formulations, including sprays and solutions, which are not approved by the agency. This alert was prompted by an increasing number of adverse event reports.
The agency highlighted potential serious risks associated with these unregulated finasteride products, urging consumers and health care providers to be cautious. The following sections break down what this FDA warning means for anyone considering topical finasteride for their hair loss.
Summary Of The April 2025 FDA Alert On Compounded Topicals
The FDA's April 2025 alert was a direct response to safety concerns surrounding compounded topical finasteride products. So, what did the FDA warning say about topical finasteride for hair loss? The agency announced it had become aware of serious adverse events reported by consumers using these non-approved treatments.
Between 2019 and 2024, the FDA’s MedWatch adverse event reporting system received 32 cases of adverse events linked to these products. The reported issues were consistent with the known side effects of oral finasteride and included:
-
Severe sexual dysfunction, including erectile dysfunction and testicular pain.
-
Neuropsychiatric issues like depression, anxiety, and suicidal ideation.
-
Persistent symptoms that continued even after patients stopped using the product.
Crucially, the FDA noted that many consumers were not made aware of these potential risks by their prescribers, with some being told the topical formulation was risk-free. This lack of transparency prompted the agency to issue a public warning about compounded topical finasteride products.
Why Certain Non-FDA-Approved Topical Sprays Were Flagged For Risk
The FDA flagged non-approved topical formulations of finasteride for several important reasons. First and foremost, these products have not undergone the rigorous evaluation for safety, quality, and effectiveness that is required for FDA approval. This lack of oversight means their performance and purity can be inconsistent.
Although topical application is intended to reduce systemic absorption, the skin can still absorb finasteride into the bloodstream. This creates a risk of the same serious side effects associated with the oral pill. Many patients who reported adverse events were told by prescribers that topical use carried no risk, which is not accurate.
Furthermore, these topical formulations pose additional risks not seen with the coated oral tablet. These include local skin reactions like irritation, dryness, and stinging. There is also a greater risk of exposure to others, such as female partners or family members, through accidental transfer of the product from the skin or hair.
What “Compounded” Means And How To Verify Safe Sources
A compounded medication is a drug that is custom-mixed by a pharmacist to fit the unique needs of a patient. Unlike mass-produced, FDA-approved drugs, compounded finasteride products are not evaluated by the FDA for safety or efficacy before they are sold. This is a key reason for the recent warning.
Because the quality and potency of a compounded medication can vary from one pharmacy to another, verifying safe sources is critical. The safest approach is to work with a licensed health care provider who prescribes the medication after a thorough consultation. They should partner with a reputable and accredited compounding pharmacy.
Avoid telehealth companies or online sellers that offer finasteride products with little to no medical oversight. A prescription should only come after a real conversation with a clinician who understands your medical history and can monitor you for any adverse event.
How Patients Can Protect Themselves From Unsafe Online Products
In the age of online pharmacies, it is easier than ever to find finasteride products, but not all sources are safe. Protecting yourself from unregulated and potentially dangerous products requires caution and awareness. The most important step is to avoid purchasing medications from websites that don't require a valid prescription from a licensed provider.
Here are some steps you can take to ensure your health and safety:
-
Always have a direct consultation with a health care provider before starting treatment.
-
Only use finasteride products prescribed specifically for you and filled by a licensed, reputable pharmacy.
-
Be wary of any platform that claims its topical finasteride is completely free of side effects or risk.
Where can I find official updates about finasteride and hair loss treatments? For the most reliable safety information, consult the FDA's website. The agency's MedWatch program is where you can report an adverse event and find the latest safety alerts on medications like finasteride.
Oral vs Topical: What’s Actually Safe?
With the recent FDA warning about topical formulations, many men are left wondering: are oral or topical finasteride products safer? The answer isn't simple. Safety depends on a combination of factors, including FDA approval, how the drug is administered, and the level of medical supervision you receive.
Both oral finasteride products and topical finasteride products have their own sets of risks and benefits. Recognizing the differences in systemic absorption and regulatory status is key to determining which path may be safer for you, in consultation with your doctor, to avoid a serious adverse event.
Comparing Systemic Absorption Between Oral And Topical Forms
The primary difference between oral and topical finasteride lies in systemic absorption, how much of the drug enters your bloodstream and circulates throughout your body. This directly influences the risk of side effects. Oral finasteride is designed for 100% systemic absorption.
Topical formulations, on the other hand, are created to minimize this. They aim to concentrate the drug in the scalp's hair follicles while keeping blood levels low. Does oral finasteride have different side effects compared to topical finasteride? While the types of side effects are similar, the likelihood of experiencing them is theoretically lower with topical use due to reduced systemic exposure.
Here’s a comparison based on clinical study data:
|
Feature |
Oral Finasteride (1mg) |
Compounded Topical Finasteride (~0.25%) |
|
Systemic DHT Reduction |
Around 70% |
Around 25-50% |
|
Scalp DHT Reduction |
Around 70% |
Around 50-70% |
|
FDA Approval Status |
Approved |
Not Approved |
|
Side Effect Risk |
Higher systemic risk |
Lower systemic risk, but still present |
Pros And Cons Of Each Route For Long-Term Treatment
When considering finasteride for long-term treatment, weighing the pros and cons of each delivery route is essential. Both oral and topical finasteride products offer potential benefits, but they also come with distinct potential adverse effects and logistical considerations.
Here’s a breakdown to help you compare:
-
Oral Finasteride:
-
Pros: FDA-approved, proven efficacy, and convenient once-a-day pill.
-
Cons: Higher risk of systemic side effects due to full absorption.
-
Topical Finasteride:
-
Pros: Lower systemic absorption, potentially reducing the risk of side effects.
-
Cons: Not FDA-approved, inconsistent quality, can be messy to apply, and risk of accidental exposure to others.
Ultimately, the choice depends on your personal risk tolerance and what you and your doctor decide is best. The guaranteed quality and known profile of FDA-approved oral finasteride products make them the standard, while topical options may be considered for specific cases under careful supervision.
When Topical Finasteride Might Be Considered Under Supervision
A topical formulation of finasteride might be a suitable option for certain people, but only under the close supervision of knowledgeable health care providers. A doctor may suggest this route for a patient who is highly concerned about the systemic side effects associated with the oral pill.
It could also be considered for someone who previously tried oral finasteride and experienced an adverse event but is still seeking an effective DHT-blocking treatment. In such cases, the goal is to achieve the hair-saving benefits while minimizing the amount of drug that enters the bloodstream.
However, this must be an informed decision. Your provider should explain that topical finasteride is not FDA-approved and discuss the risks highlighted in the recent FDA alert. If you proceed, it is vital to use a product from a trusted and reputable compounding pharmacy to ensure you are getting a quality formulation.
Why FDA-Approved Formulations Remain The Gold Standard
FDA-approved medications are considered the gold standard for a simple reason: they have been rigorously vetted for safety, quality, and effectiveness. Is topical finasteride currently FDA-approved for treating hair loss? No, it is not. Only oral finasteride (1mg, brand name Propecia and its generics) has FDA approval for this purpose.
Here’s what FDA approval guarantees:
-
Proven Efficacy: The drug has been proven to work for its intended use in large-scale clinical trials.
-
Verified Safety Information: The potential side effects and risks have been identified and are clearly listed on the label.
-
Consistent Quality: Every batch of the medication is manufactured under strict standards to ensure consistent potency and purity.
This level of oversight is absent with non-approved, compounded finasteride products. While some may be effective, their quality is not guaranteed, and the full risk profile is not as well-established. For this reason, health care providers typically recommend starting with the FDA-approved option.
Who Should Avoid Finasteride

Finasteride is a powerful medication and is not a suitable hair loss solution for everyone. There are specific contraindications and warnings that make the drug unsafe for certain people. It’s important to be aware of these restrictions to prevent a serious adverse event.
Before considering any finasteride products, you must review your health status with your health care provider. Women, especially those who are pregnant, and those with certain hormone conditions should avoid this medication. We will explore these contraindications in more detail below.
Contraindications Related To Pregnancy And Hormone Conditions
The most critical contraindication for finasteride relates to pregnancy. Who should avoid using finasteride based on the FDA’s recommendations? Women who are pregnant or may potentially become pregnant must not use or handle finasteride products.
This is because the medication can be absorbed through the skin and cause serious birth defects in a developing male fetus, specifically abnormalities of the external genitalia. For this reason:
-
Pregnant women should not take finasteride.
-
They should not handle crushed or broken finasteride tablets.
-
They should avoid contact with topical finasteride solutions due to the risk of inadvertent exposure.
Beyond pregnancy, people with certain pre-existing hormone conditions should discuss the use of finasteride carefully with their doctor. Because the drug works by altering hormone levels, it could potentially worsen or interfere with other hormonal issues. Full disclosure of your medical history is essential for safety.
Why Finasteride Isn’t Appropriate For Some Younger Men Or Women
Finasteride is generally not prescribed for women or adolescent males. For women, the primary concern is the risk to a male fetus during pregnancy. Even for women not planning a pregnancy, doctors typically recommend other hair loss treatments first, as finasteride is not FDA-approved for female pattern hair loss and can disrupt their natural hormone balance.
For younger men, particularly those still in their teens, finasteride is usually avoided. The drug’s mechanism of altering testosterone conversion can interfere with the final stages of sexual development. Health care providers are cautious about prescribing hormone-altering medications during this important developmental period.
Ultimately, the decision to use finasteride products must be based on careful medical advice. For both women and younger men, the potential risks often outweigh the benefits, and alternative treatments for hair loss are typically explored first.
Medical History Factors To Review With Your Clinician First
Before you start taking finasteride, a thorough review of your medical history with your clinician is mandatory. Being completely transparent about your health is the best way to avoid potential adverse effects and ensure the treatment is safe for you.
Your health care provider will need to know about any past or present conditions. Be sure to discuss if you have a history of depression, anxiety, suicidal thoughts, or any other mental health concerns, as finasteride has been linked to neuropsychiatric side effects.
Other important factors to review include any history of liver disease, as the liver is responsible for processing the drug. You should also mention any existing sexual health issues, such as erectile dysfunction or low libido. Finally, provide a complete list of all other medications and supplements you are taking to check for potential interactions with finasteride products.
Talk To Healthon About Safe Treatment Options

Navigating the world of hair loss treatment can be confusing, especially with conflicting information online. Instead of relying on impersonal telemedicine platforms or "cloud pharmacies," it's better to seek guidance from qualified health care providers who prioritize your safety.
At Healthon, you can connect with clinicians who provide personalized and safe treatment plans. We believe in transparent communication about finasteride and other hair loss treatments, ensuring you are a partner in your own health journey. We are here to help you find a solution that is both effective and responsible.
How Healthon Clinicians Personalize Finasteride And Combination Plans
At Healthon, we don't believe in a one-size-fits-all approach to hair loss. Our telemedicine platform connects you with real health care providers who take the time to understand your unique situation. Your journey begins with a thorough consultation where you can discuss your hair loss, goals, and any health concerns.
Based on this evaluation, your clinician will create a personalized hair loss treatment plan tailored to you. This plan is built on a foundation of safety and efficacy. Your options may include:
-
Prescribing FDA-approved oral finasteride if it's a good fit for you.
-
Developing a combination therapy plan, such as pairing finasteride with topical minoxidil for enhanced results.
-
Providing guidance on lifestyle factors that support healthy hair.
Unlike other platforms, we focus on creating a sustainable, long-term strategy. Our goal is to prescribe finasteride products responsibly, ensuring you receive the highest standard of care.
Monitoring Protocols To Minimize Risk And Side Effects
Your safety is our top priority. When you start a treatment plan with Healthon, you are not left on your own. We have established robust monitoring protocols to minimize risk and manage any potential side effects of finasteride products.
Our health care model includes regular follow-ups with your clinician. These check-ins are an important opportunity to discuss your progress, ask questions, and report any changes in your health. This continuous loop of communication allows us to catch any potential issues early.
If you experience any concerning symptoms, our health care team is accessible to provide guidance. This proactive approach to monitoring ensures that your hair loss journey is managed responsibly from start to finish, giving you peace of mind as you work toward your goals.
Next Steps For Evaluating Your Hair-Loss Treatment Safely
Are you ready to take control of your hair loss safely and effectively? The next step is to get professional medical advice from a qualified clinician. A proper evaluation is the foundation of any successful hair loss treatment plan.
We invite you to start a consultation with one of Healthon's experienced health care providers. During your visit, you can have an open conversation about your concerns, learn about your options, and determine if finasteride products are the right choice for you.
Don't navigate this journey alone or rely on questionable online sources. Partner with a team that puts your health first. Schedule your consultation today to get a personalized, safe, and effective plan to address your hair loss.
Frequently Asked Questions
What Are The Main Side Effects Of Finasteride For Hair Loss?
The main side effects of finasteride for hair loss include sexual dysfunction (such as erectile dysfunction and low libido) and neuropsychiatric issues like depression, anxiety, and "brain fog." These adverse effects can occur with both oral finasteride and topical formulations, though the risk may be lower with topical use.
Are There Alternatives To Finasteride That Are Safe And Effective?
Yes, there are several effective alternatives to finasteride. Topical minoxidil is another FDA-approved hair loss treatment that works by stimulating hair growth. Other options include low-level laser therapy, platelet-rich plasma (PRP) injections, and nutritional supplements. A healthcare provider can help you choose the best alternative based on your needs.
Who Should Avoid Using Finasteride Based On Recent FDA Recommendations?
Based on contraindications and FDA warnings, women who are or may become pregnant must avoid all finasteride products due to the risk of birth defects. People with a history of depression or other mental health conditions should also discuss the risks carefully with their health care provider before starting treatment.
What Sexual Side Effects Can Occur With Finasteride?
Finasteride products can cause sexual side effects including decreased libido, erectile dysfunction (ED), and issues with ejaculation. For some men, these issues have been reported to continue even after they stop taking the medication, a condition sometimes referred to as persistent sexual dysfunction.
What Happens After Stopping Finasteride?
After you stop drug administration of finasteride, its DHT-blocking effect ceases. Your hair loss will likely resume, and any hair you regrew or maintained will probably fall out over the next year. Most adverse effects resolve after stopping, but in some reported cases, they have persisted.
Can I Combine Finasteride With Minoxidil?
Yes, combining oral finasteride with topical minoxidil is a very common and effective hair loss treatment strategy. They work through different mechanisms to prevent hair loss and promote regrowth, often leading to better results together than either one alone. Always consult your health care provider before starting a combination therapy.
Reference List
-
Bauman Medical. (2025). FDA warning on topical finasteride: Holistic treatment options. Bauman Medical. https://www.baumanmedical.com/fda-warning-topical-finasteride-holistic-treatment-options/
-
CBC News. (2025, April). FDA warns about risks of topical finasteride products. CBC News. https://www.cbc.ca/news/health/topical-finasteride-risks-fda-u-s-1.7530877
-
Epocrates. (2025). FDA warns of risks with compounded topical finasteride. Epocrates. https://epocrates.com/online/article/fda-warns-of-risks-with-compounded-topical-finasteride
-
Food and Drug Administration. (2025a). FDA alerts health care providers, compounders, and consumers to potential risks associated with compounded topical finasteride. U.S. Food & Drug Administration. https://www.fda.gov/drugs/human-drug-compounding/fda-alerts-health-care-providers-compounders-and-consumers-potential-risks-associated-compounded
-
Food and Drug Administration. (2025b). Human drug compounding: Regulatory framework and safety guidance. U.S. Food & Drug Administration. https://www.fda.gov/drugs/human-drug-compounding/fda-alerts-health-care-providers-compounders-and-consumers-potential-risks-associated-compounded
-
Healthline. (2025). FDA warning: Hair loss treatment and topical finasteride risks. Healthline. https://www.healthline.com/health-news/fda-warning-hair-loss-treatment-topical-finasteride
-
Healio Dermatology. (2025, May 8). Counseling patients on safe hair loss options after FDA’s finasteride warning. Healio. https://www.healio.com/news/dermatology/20250508/qa-counseling-patients-on-safe-hair-loss-options-after-fdas-finasteride-warning
-
Horizon Blue Cross Blue Shield. (2025). FDA alerts health care providers, compounders, and consumers about compounded topical finasteride risks. Horizon Blue. https://www.horizonblue.com/members/news/member-news/fda-alerts-health-care-providers-compounders-and-consumers-potential-risks-associated-compounded
-
Mayo Clinic. (2025). Finasteride (oral route): Description and safety information. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/finasteride-oral-route/description/drg-20063819
-
Powers Health. (2025, April 24). FDA warns of unapproved hair loss product linked to side effects. Powers Health. https://www.powershealth.org/about-us/newsroom/health-library/2025/04/24/fda-warns-of-unapproved-hair-loss-product-linked-to-side-effects
-
Pharmacist.com. (2025). Potential dangers of using finasteride for hair loss in males. American Pharmacists Association. https://www.pharmacist.com/Blogs/CEO-Blog/potential-dangers-of-using-finasteride-for-hair-loss-in-males
-
PubMed Central. (2024). Systemic absorption and pharmacokinetics of topical finasteride in androgenetic alopecia. Journal of Clinical and Aesthetic Dermatology, 17(2), 10172713. https://pmc.ncbi.nlm.nih.gov/articles/PMC10172713/
-
U.S. Food & Drug Administration. (2025). Compounded topical finasteride: Official alert and safety update. U.S. Food & Drug Administration. https://www.fda.gov/drugs/human-drug-compounding/fda-alerts-health-care-providers-compounders-and-consumers-potential-risks-associated-compounded
-
Xyon Health. (2025). Is topical finasteride FDA approved? Xyon Health. https://xyonhealth.com/blogs/library/is-topical-finasteride-fda-approved
- EMPR. (2025). Concerns over compounded topical finasteride prompt FDA alert. EMPR. https://www.empr.com/news/concerns-over-compounded-topical-finasteride-prompt-fda-alert/








