What is NAD? Here’s What You Need To Know

The growing interest in nicotinamide adenine dinucleotide (NAD+) can now be seen in health and wellness all over the world. This coenzyme is used by the body for important jobs like energy production, DNA repair, supporting the immune system, and stopping damage caused by oxidative stress, contributing to better skin health.
Preliminary studies in mouse models have shown that as new research shows more about how important it is, NAD+ is getting a lot of attention for helping with aging, metabolic disorders, and improving mental health.
People now use different ways, from supplements to IV therapies, to help the body be healthy at the cell level. Because of this, NAD+ is seen as a good option that could help people have better health for many years.NAD stands for nicotinamide adenine dinucleotide. It has become well-known in the health and wellness field in recent years.
This important coenzyme helps with many things in your body, like energy production in your cells and DNA repair. As more people hear about what it can do, many are thinking about taking NAD supplements. They hope it can help with their overall health, fighting the signs of aging, and increasing energy levels. Wellness clinics and biohackers talk a lot about using NAD. Because of this, it is a good time to learn what NAD is and how it might help with your well-being.
What Is NAD (And NAD+)?
NAD is important because it helps with many cellular processes that are crucial for human health. It is a coenzyme and comes in two forms, NAD+ and NADH. NAD+ is key in redox reactions, where it helps move electrons and supports mitochondrial function.
This action helps our cells make energy by turning what we eat into fuel our bodies can use. As we get older, there is a decline of NAD in our bodies, and this is linked to lower energy levels. Knowing how NAD works is important for keeping good health and feeling your best. When you understand the basic science behind NAD, you begin to see how vital and helpful it is in our daily lives.
What is NAD, NAD+, and NADH
Nicotinamide adenine dinucleotide, or NAD, is an important helper molecule that plays a vital role in cellular metabolism and is crucial in conditions like mitochondrial dysfunction. The salvage pathway significantly impacts NAD and the role of NAD levels, as NAD comes in three forms: NAD, NAD+, and NADH, which are necessary to boost NAD+ levels. NAD+ is the form needed for different tasks in the body, like energy production and DNA repair.
NADH is the reduced form, and it also works in redox reactions with NAD+. There needs to be a balance between NAD+ and NADH for everything to work well. This is very important for places like skeletal muscle and the brain, where the body needs a lot of energy. This is why NAD matters to our health.
What Does NAD Do in the Body?
Effective metabolism depends on nicotinamide adenine dinucleotide (NAD+), including nicotinic acid mononucleotide and nicotinic acid adenine dinucleotide, to make sure there is good energy production in our cells. Think of NAD+ as the "cellular fuel helper." It works non-stop in the mitochondria, which are the powerhouses in our cells.
NAD+ plays a big part in turning nutrients, including amino acids, into adenosine triphosphate (ATP), and the de novo synthesis of NAD+ is crucial for maintaining this energy production. ATP is what gives energy to many of our body’s functions.Because NAD+ helps with redox reactions, it also supports paths that help restore other important things that keep our energy levels up, including muscle function.
This teamwork between NAD+ and mitochondrial function is key for keeping up good energy and fighting chronic fatigue and tiredness. So, it is very important for our overall health.
Why Is NAD Important for Health?

NAD is very important for the body. It helps the cells make energy from nutrients, which turns into ATP. This gives you the power to do things every day. NAD also helps with DNA repair. It can lower oxidative stress and keeps you feeling your best. This makes NAD key for wellness and for staying healthy as you get older.
Support Cellular Energy Production
Cellular energy production needs NAD+ to work well. This important coenzyme helps the body use food and turn it into ATP, which is like fuel for your cells. NAD+ works like a helper, making sure energy gets made as your body needs it. If levels of NAD+ drop, you may feel tired, and your physical performance can go down.
This is common in older adults. Keeping good levels of NAD+ not only helps with energy production but also helps mitochondrial function. When your mitochondria work well, your overall health and energy levels get better. Making sure you have enough NAD+ can help you feel more energetic and full of life.
NAD+ helps change food into ATP. ATP is the main way our cells get energy. This process is important for keeping good energy levels, especially when you feel worn out or tired. NAD+ helps with redox reactions and different body processes to make sure your body uses carbs, fats, and proteins well.
If NAD+ drops, there can be less ATP, which makes you feel tired and low on energy. So, it is important to keep your NAD+ up to help fight tiredness and keep your body full of energy.
Plays a Role in Healthy Aging

The decline of cellular NAD+ is linked to the aging process and the adverse effects of NAD+ deficiency, including the depletion of NAD+, which can affect overall health as people get older. NAD+ is an important coenzyme in the body.
It helps keep cells working well, supports DNA repair, and helps with how your body uses energy. When NAD+ levels go down, the body has a harder time dealing with oxidative stress. It also gets weaker at fixing cells. This may cause signs of aging. It can also make people more likely to get diseases related to aging. Raising NAD+ levels with supplements could help people age in a healthier way. It might also help the body work well for longer as we grow older.
NAD+ is very important in how sirtuins work, as sirtuins are NAD+/NADH-dependent enzymes that are tied to living longer and keeping cells healthy. As people get older, the levels of NAD+ in their bodies go down. This can slow down sirtuin activity and have an effect on the aging process. When these levels of NAD+ drop, it also affects things like DNA repair and how the body uses energy through cellular metabolism.
This can cause more oxidative stress and can lead to age-related diseases. By looking at how NAD+ and sirtuins work together, we can see why it matters to keep the levels of NAD+ up. It helps with fighting the signs of aging and staying healthier as we age. That is why a lot of research on aging and new treatments focus on NAD+ and how it affects people.
Helps Repair DNA and Fight Oxidative Stress
Keeping our cells strong depends on good DNA repair. NAD+ helps with this. This important coenzyme boosts the work of sirtuins and repair enzymes. They are needed to fix DNA damage that comes from oxidative stress. NAD+ is also key for cellular metabolism. It helps the body fight things that speed up aging and disease.
When the body has enough NAD+, research shows it can help improve immune response and support cell survival. This leads to better overall health. Seeing how NAD+ connects to these things shows how important it is. It helps the body fight premature aging and keeps our cells safe.
DNA repair is very important for cells. It keeps the genetic code safe from harm that can happen from things in the environment and from what happens in the body every day. NAD+ is key here. It works as a helper for enzymes like PARPs that take part in fixing DNA repair.
When you have enough NAD+, it helps fix single-strand breaks fast and cuts down on damage from oxidative stress. This keeps cells from getting hurt. In this way, NAD+ makes DNA repair work better and helps the body stay healthy and strong when faced with age, damage, and disease.
What Is NAD IV Therapy?
Delivering NAD+ straight into the blood using an IV is starting to be more common in wellness. This way helps the body take in NAD+ right away. More people like biohackers and some wellness clinics are using it, as they see it as easy and helpful. Some people say it boosts their energy levels, makes them think more clearly, and helps with detox.
Even though this sounds good, the way it works can be different for everyone and there is not much strong research on it yet. So, we still need more studies to fully know how well it works and not make any strong medical claims about it.
If you want to learn more about NAD therapy and the benefits of NAD and how it might help, you should check out this helpful article. It talks about the different good things tied to NAD therapy, with a focus on how it can boost your day-to-day energy levels, overall health, and potential side effects. When you know about these benefits, you can choose if using NAD supplements or NAD IV therapy is right for you and your routine.
The details given offer a useful guide if you want to support your body’s cell work, lift your energy, or improve your overall health. See how NAD therapy may be the next step if you want to feel good and full of life.
NAD IV Therapy vs. Supplements
Both NAD IV therapy and taking oral supplements come with their own good and bad points. NAD IV therapy can help your body take in NAD quickly, which may give you higher energy right away. But this option can take a lot of time, and you often need to go to a clinic for the treatment. On the other hand, NAD+ supplements, like the ones from Healthon, are easy to use.
You can take them at home anytime, which is more simple for most people. If you take these supplements on a regular basis, it can help support your energy levels and your overall health. You will not need a doctor to watch over you. IV therapy may show its effects fast, but Healthon’s supplements make it simple to add NAD+ to your daily wellness routine.
Who Might Benefit from NAD Supplementation?

NAD+ supplements may help support wellness for different groups, especially people over 30. As people get older, their NAD levels can drop. This may lead to tiredness and trouble thinking clearly. People might want to boost their energy and focus by using NAD+.
Some people who want healthy aging or a longer life may choose NAD+ for their daily routine. Living with a lot of stress can also lower NAD levels and hurt overall health. While this does not promise medical results, many are trying NAD+ as a way to help their wellness and feel more energetic.
Why Choose Healthon’s NAD+ Supplement?
Unlock the chance to improve your health with NAD+ supplements, as talked about in this blog. We have seen that NAD+ is very important for things like energy in cells, how your body uses food, and the aging process. If you want help on your health journey, Healthon is here for you anytime, day or night. You always have support when choosing what is best for your health.
Take a look at our NAD supplement options. Find the one that fits your needs and learn how you can raise your NAD+ levels in a good way. If you have any questions, you can contact us through our contact page or see our NAD products.
Frequently Asked Questions
Is NAD+ safe to take?
NAD+ supplementation as a dietary supplement is usually safe for most people in the United States when you take it as told. But people can react in different ways, especially at high doses. It is a good idea to talk to a healthcare provider or professional before you start using any new supplement, especially if you have health problems or worries.
How do I increase NAD+ naturally?
To help your body get more NAD+ in a natural way, try to exercise often and eat a healthy diet. Make sure your food gives you enough vitamins B3 and E. You can also try going without food for short times, as with intermittent fasting. It is good to get enough sleep and keep your stress under control. All of these steps can work well to raise the amount of NAD+ your body makes.
What are the benefits of taking NAD+ supplements?
NAD+ supplements can help boost your energy levels, especially if you're experiencing symptoms of low NAD+. They support how your body handles food and help with cell repair. These supplements may also help lower tiredness and help your mind work better, which is called cognitive function, potentially reducing risks of cognitive disorders like Parkinson’s disease.
Moreover, they may also help in managing Parkinson’s disease, contributing to improving cardiovascular health by potentially lowering blood pressure. This makes them a good choice for people who want to feel better and live longer. You can read more about these benefits in our upcoming NAD benefits blog.
What is NAD IV therapy used for?
NAD IV therapy is mainly used to help boost energy levels, help the body with detox, and help you think more clearly by improving circulation through blood vessels. Many people who are into biohacking and some wellness clinics like to use it.
Even though doctors do not make health promises about it, people say it may have good results. This makes NAD IV therapy a good choice for those who want help with their general wellness.
Reference List
-
Bogan, K. L., & Brenner, C. (2008). Nicotinamide adenine dinucleotide (NAD+) metabolism and function. Annual Review of Nutrition, 28, 115–130. https://www.nature.com/articles/s41580-020-00313-x
-
Bryant University. (2024). Are anti-aging NAD supplements safe? Bryant expert unpacks science behind rising trend. https://news.bryant.edu/are-anti-aging-nad-supplements-safe-bryant-expert-unpacks-science-behind-rising-trend
-
CNBC. (2025, March 11). NAD+ is the latest trendy anti-aging supplement. What do doctors say? https://www.cnbc.com/2025/03/11/nad-is-the-latest-trendy-anti-aging-supplement-what-do-doctors-say.html
-
Creative Proteomics. (2023). Nicotinamide adenine dinucleotide metabolite analysis. https://www.creative-proteomics.com/resource/nicotinamide-adenine-dinucleotide-metabolite-analysis.htm
-
Delmarva Pain. (2023). What is NAD+ and why is it so popular? https://www.delmarvapain.com/blog/what-is-nad-and-why-is-it-so-popular
-
Health.com Editors. (2023). What is NAD+? Benefits and risks. https://www.health.com/nicotinamide-adenine-dinucleotide-nad-8657809
-
National Center for Biotechnology Information. (2021). NAD+ supplementation and neurodegeneration. Frontiers in Aging Neuroscience. https://pmc.ncbi.nlm.nih.gov/articles/PMC7963035/
-
National Center for Biotechnology Information. (2022). NAD+ and age-related diseases. Journal of Molecular Sciences. https://pmc.ncbi.nlm.nih.gov/articles/PMC9512238/
-
National Center for Biotechnology Information. (2015). NAD+ and cellular energy. https://pmc.ncbi.nlm.nih.gov/articles/PMC4487780/
-
National Center for Biotechnology Information. (2023). Sirtuin activity requires NAD+. https://pmc.ncbi.nlm.nih.gov/articles/PMC7973386/
-
National Institutes of Health. (n.d.). Nicotinamide adenine dinucleotide. https://www.ncbi.nlm.nih.gov/
-
Nature. (2020). NAD+ signaling in aging and disease. https://www.nature.com/articles/s41392-020-00311-7
-
Nature. (2020). NAD+ supplementation enhances mitochondrial function. https://www.nature.com/articles/s41392-020-00354-w
-
ScienceDirect. (2022). The roles of NAD in metabolism and cell function. https://www.sciencedirect.com/science/article/pii/S0006295222000405
-
Verywell Health. (2023). What is NAD? Uses, benefits, and more. https://www.verywellhealth.com/what-is-nad-7561299
-
Wikipedia. (n.d.). Nicotinamide adenine dinucleotide. https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide
- Cell & Bioscience. (2023). NAD+ in cellular signaling pathways. https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-023-01031-5
Longevity
NAD+

From $165.00
Longevity
NAD+

From $165.00
Healthon’s NAD+ Longevity Program offers cutting-edge anti-aging therapies to support cellular health and overall vitality. By targeting aging at the molecular level, NAD+ helps restore energy, improve cognitive function, and promote youthful longevity. With two delivery methods—vial injection and nasal spray—you can choose the option that works best for your lifestyle. Backed by science, NAD+ is becoming a cornerstone in the quest for healthier aging.
Longevity
Metformin

From $
Longevity
Metformin

From $