Vyleesi Side Effects: What to Expect from PT-141 for Women

It is important for many women to know more about the different parts of female sexual dysfunction. Vyleesi, which people also call bremelanotide, is a name known for helping treat hypoactive sexual desire disorder. But, like other drugs, it can bring some Vyleesi side effects that people need to think about.
This blog will go over both the common and rare side effects that can happen with Vyleesi, giving a clear picture of what to expect while using it. Learning about these side effects can help women make better choices when working to improve their sexual health and deal with health problems related to sexual dysfunction, sexual desire disorder, and other issues like low sexual desire.
Having an easy roadmap helps you navigate the details of Vyleesi effectively. Below is an overview of the topics this guide will cover to ensure comprehensive information is at your fingertips:
Read on to explore how Vyleesi works, who should consider it, and what alternatives exist for women seeking non-branded choices like Healthon’s PT-141 peptide.
What Is Vyleesi (PT-141)?

Vyleesi, which is also called bremelanotide, is a new synthetic peptide that has been approved by the FDA for women who do not yet have menopause and have hypoactive sexual desire disorder. This medication is different because it works by turning on melanocortin receptors in the brain. It can help with sexual arousal and sexual desire, not by changing your hormone levels, but by targeting the nervous system.
Vyleesi gives a new way to help women who have low sexual desire or problems with sexual desire disorder. If you learn about how it works, you can be more informed when looking for good answers about sexual satisfaction from your health care provider.
If you want to know more about Vyleesi and PT-141, the Healthon PT-141 guide can help you get started. This easy-to-read article looks at the science behind bremelanotide, shows you how safe it is, and talks about how it stacks up against other options.
The guide will show you how PT-141 and treatments like Vyleesi are used for HSDD. It also explains how doctors work with each person to get the best results. After reading this, you will see the medical advice and how to use these treatments more clearly.
Check out our guide to see how it compares to prescription picks like Vyleesi. You will find it offers both flexibility and good prices. If you want to know more about handling side effects or how there may be more uses, this link helps fill in what you need to know. It gives you the information you need to make good choices for your health.
How Is Vyleesi Used?
Administering Vyleesi is done with an auto-injector. You use it for a shot under the skin, usually in the abdomen or thigh. This way is made to be easy, so you can do it yourself while keeping it out of the reach of children.
For the best results, you should take the medicine about 45 minutes before you take part in sexual activity. Do not use more than one injection in 24 hours. Also, do not go over eight doses in one month. Always follow the instructions given to you. Doing this can help lower the chance of possible side effects.
Common Side Effects of Vyleesi

Common side effects that people report in clinical trials include:
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Nausea: This is common after taking the medicine. The feeling can start soon, but you can often handle it with changes in what you eat.
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Flushing: Many people get a feeling of warmth, mainly on their face. This blood flow increase is normal.
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Injection site reactions: You might get pain, redness, or swelling where you get the injection. These are mild and usually do not last long.
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Headache: Some people get headaches. This may happen because the medicine changes blood pressure or how the nervous system works.
Knowing about these side effects can help you and your doctor make good choices about Vyleesi use.
Rare and More Serious Side Effects
Most people do well when they use Vyleesi, but there can be some serious side effects, even if they are not common. One thing to watch for is a rise in blood pressure. This could cause problems for people who already have heart disease or heart issues. Some might feel sick to their stomachs and may even need medicine to help with this.
There can also be skin changes, like the gums or skin turning darker, but this does not happen often. It is important to know these potential risks. If you see any of these side effects, make sure to talk to your healthcare provider right away.If you want to really understand Vyleesi, you should read the FDA's official label. You can find this document at FDA Vyleesi Label. It tells you all you need to know about how Vyleesi was approved, how to use it, and what potential side effects can come from using bremelanotide.
This helps people and their doctors stay well-informed about both the good points and the risks of this treatment. Learning this is very important for anyone looking to take care of hypoactive sexual desire disorder or any sexual desire disorder the right way. Being aware of side effects is a big part of making the best choice for you.
Who Should Avoid Vyleesi?
Some health conditions may mean you should not use Vyleesi. This is true if you have uncontrolled high blood pressure, heart problems, or serious liver disease, including issues related to blood vessels. If you have any of these, you need to be careful. Vyleesi can make these health issues worse and could lead to more problems.
It is very important to check all of your medical history, including any herbal products, with your healthcare provider before starting Vyleesi. Talk with your doctor before you begin taking it. This will help both you and your healthcare provider find a safe way to manage sexual desire disorder, like hypoactive sexual desire disorder. It also helps lower any potential risks with Vyleesi, and takes your other health needs into account, including any issues with liver disease.
Exploring other choices like Healthon for PT-141 can help people get new ideas and support. Healthon focuses on safety and making sure things work well. You get advice from real medical experts. This group makes medical advice easy to get.
They talk about possible side effects of bremelanotide and what you can expect from the effects of bremelanotide. If you speak to their team, you will know more about your options. They also give you advice that fits your own health conditions. When you get good information, you can make the right choices. This can help with sexual performance and can make you feel better overall.
PT-141: A Gentler Alternative to Prescription Vyleesi
Healthon’s PT-141 peptide is a good choice for people who want to improve sexual desire without paying high prices for brand name Vyleesi. This option gives people the same active ingredient, bremelanotide, that works on the body’s melanocortin receptors to help with sexual desire. You do not have to pay extra for fancy branding. Instead, you get a more affordable option that still works well for those with sexual desire disorder.
Healthon’s PT-141 lets you change the dose as needed, so it fits different needs. The treatment is made for premenopausal women with hypoactive sexual desire disorder. By keeping costs lower and making the product easy to get, Healthon focuses on both doing a good job and being priced right for all.
Healthon’s PT-141 peptide is a good choice when you compare it to brands like Vyleesi. It has the same active ingredient, bremelanotide, but it gives you more options at a better price. You get the same results, but you can save money with the way Healthon works.
This is great for people who want to increase their sexual desire in a way that fits their life. Healthon focuses on quality too. So, you can be sure that you get treatment that works well and has fewer potential side effects than those found with more expensive prescriptions and less affordable options.
Tips for Minimising Side Effects
Engaging with Vyleesi needs care to help lower side effects and potential side effects. It’s good to drink a lot of water. This can help with nausea and stop other problems. Try to take the shot with food. This may make it easier on your body. Start with a low dose and see how you feel. You can then change the dose if needed.
Write down any side effects or potential side effects you get, so you can talk about them with your doctor or nurse. Always make sure to get Vyleesi from good places like Healthon for your safety and trust.
If You’re Unsure, Speak To A Healthon Expert!
Handling hypoactive sexual desire disorder and learning about Vyleesi can be tough. Healthon is here to help you all day, every day. We have experts to guide you and help you learn more about the effects of bremelanotide.
They can also help you with the possible side effects. Our team answers all your questions, so you feel ready and supported at each step. If you want to know more or see what we offer, go to our contact page. You can also find our PT-141 product for women at https://healthon.com/products/bremelanotide-pt-141-women. With us, your way to better sexual arousal and more about sexual desire or sexual desire disorder is always close by.
Frequently Asked Questions
How long do Vyleesi side effects last?
Vyleesi side effects often last only a few hours, but the way that people feel them can be different. The most common side effects, such as feeling sick to your stomach or having a red face, as well as a stuffy nose, usually get better in a day. If these common side effects do not go away or get worse, it is important to get in touch with a healthcare provider for more help.
Is Vyleesi safe to use regularly?
Vyleesi (PT-141) may be safe to use often, but people can react in different ways. You should talk with a healthcare provider about your health conditions and discuss any potential risks, including those that may affect an unborn baby. It is a good idea to see your healthcare provider regularly. This helps to check for side effects, watch how well the medicine works, and keep you safe.
Vyleesi (PT-141) is mostly used for something other than weight gain or weight loss. But some people who use it may see a change. This is because it can change how they feel, including their well-being and want for sex. If you want to know more about how it might play a part in managing weight, you can check out the article linked here.
What’s the difference between Vyleesi and PT-141?
Vyleesi is the brand name for bremelanotide. It is a prescription treatment for women who have low sexual desire. PT-141 is the same active ingredient as Vyleesi. The two may come in different forms. Both are used to help raise sexual desire in women. Vyleesi is controlled and checked carefully. PT-141 can sometimes be a way for people to get another option.
Reference List
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Food and Drug Administration. (2019). Bremelanotide injection label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210557s000lbl.pdf
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Meston, C. M., & Frohlich, P. F. (2020). PT-141: Review of melanocortin receptor agonists. Journal of Sexual Medicine, 17(2), 259–267. https://pmc.ncbi.nlm.nih.gov/articles/PMC6819023/
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Clayton, A. H., & Kingsberg, S. A. (2019). Bremelanotide for HSDD in premenopausal women. Journal of Women’s Health, 28(9), 1262–1271. https://pmc.ncbi.nlm.nih.gov/articles/PMC6819021/
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Mayo Clinic. (2024). Bremelanotide (subcutaneous route). https://www.mayoclinic.org/drugs-supplements/bremelanotide-subcutaneous-route/description/drg-20466805
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Healthline. (2023). Tadalafil oral tablet: Side effects and interactions. https://www.healthline.com/health/drugs/tadalafil-oral-tablet
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U.S. FDA. (2019). Vyleesi prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210557s000lbl.pdf
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PMC. (2020). Pharmacodynamics and pigmentary changes from bremelanotide. https://pmc.ncbi.nlm.nih.gov/articles/PMC6819023/
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Healthon. (2025). PT-141 for women. https://healthon.com/products/bremelanotide-pt-141-women
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Mayo Clinic. (2023). Usage guidelines for PT-141. https://www.mayoclinic.org/drugs-supplements/bremelanotide-subcutaneous-route/description/drg-20466805
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Healthline. (2022). How to manage side effects of PT-141. https://www.healthline.com/health/drugs/tadalafil-oral-tablet
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FDA. (2020). Administration and dosing instructions. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210557s000lbl.pdf
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PubMed Central. (2021). Clinical trials of bremelanotide. https://pmc.ncbi.nlm.nih.gov/articles/PMC6819021/
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Mayo Clinic. (2024). Drug overview: Bremelanotide. https://www.mayoclinic.org/drugs-supplements/bremelanotide-subcutaneous-route/description/drg-20466805
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Healthon. (2025). Prescription alternatives and expert support. https://healthon.com/products/bremelanotide-pt-141-women
- FDA. (2019). Detailed drug label for Vyleesi. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210557s000lbl.pdf
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