Can Mounjaro Cause Blood Clots? What You Need to Know

If you are looking into Mounjaro, which is a medication given to people with type 2 diabetes, you might worry about the possible side effects. One big concern for many people is the chance of a blood clot or venous thromboembolism (VTE), along with deep vein issues. This worry comes from research published in the Endocrine Journal with other drugs in the same group, like semaglutide, that showed there could be an increased risk of things like deep vein thrombosis (DVT) and problems like that. 

There is not a clear answer from clinics or doctors yet about if tirzepatide has a direct link to blood clots and DVT risk. But with lawsuits and the way doctors are keeping an eye on Mounjaro users who take Mounjaro, it does raise questions. Should you be worried about DVT or even a pulmonary embolism (PE) when you take Mounjaro? What can you do to lower your risk if you use this medicine?

This blog will look at what doctors know about Mounjaro and how big or small your blood clot risk might be. We will show what is known so far about how safe the drug is, including the legal action that has been taken regarding its side effects and the amount of time it takes to process these cases. Also, we will talk about other choices, like Healthon’s compounded tirzepatide. Our goal is to clear up some of the confusion, talk about the facts, and help you and others make better choices.

What Is the Link Between Mounjaro and Blood Clots?

There is no proven link right now between Mounjaro (tirzepatide) and blood clot problems. Some side effects may have to do with the heart and blood flow. But blood clots are not on the list of known side effects. There are still new studies going on that want to see if there could be any ties in the future.

What Are Blood Clots and Why Are They Dangerous?

Blood clots are clumps of blood that can block normal blood flow in the body. These clots can be dangerous for your health. Deep vein thrombosis happens when a blood clot forms in a deep vein, usually in the legs. This can cause pain and swelling in that area. If the clot breaks free, it may travel to the lungs. When this happens, it can cause a condition called pulmonary embolism. This is very serious and can be life-threatening.

It is important to know about these things. You should watch for signs like swelling and shortness of breath. These could be clues that there are deep vein problems or a blood clot forming. If you notice these signs, you need to get medical help right away.

What Causes Blood Clots?

Blood clots can happen because of many things that can stop blood from moving easily in the body. Most times, this is due to changes in blood flow, problems with blood vessels, or how the blood makes clots.

Some physical health conditions, like obesity or injuries to the blood vessels, can make it easier for a clot to form. This can also happen when a person gets dehydrated. For example, dehydration that comes from gastrointestinal side effects, like vomiting from delayed gastric emptying due to taking GLP-1 receptor agonists, makes the blood thicker. This higher thickness can raise the chance of a blood clot.

For some people, being born with certain genes can put them at higher risk. For example, if someone has an inherited issue like the Factor V Leiden mutation, the chance of clotting can go up a lot. If we know the health conditions that can lead to this, then good steps can be taken to help prevent blood clots.

Lifestyle and health choices have a big effect on the chance of developing blood clots. Here are some common things that can raise your risk:

• Prolonged immobility: If you sit for a long time, like on long flights or because of a job, blood does not flow well. This can help clots form.

• Obesity: Having extra weight adds stress to the veins and slows down blood flow.

• Smoking: Using tobacco is bad for blood vessels and can raise the risk of clots.

• Hormone therapy: Taking birth control pills or hormone replacement can change how the blood clots.

• Family history: If anyone in your family has a problem with clotting, you could be more likely to get clots too.

Those with other issues, like diabetes or cardiovascular disease, have a higher chance of blood clots. Some medicines, such as Mounjaro, can increase this risk. It is important for people at risk to move their bodies when they can and focus on healthy habits to help with blood flow and weight loss.

Is There Clinical Evidence Linking Mounjaro to Blood Clots?

The 2022 FDA documentation for tirzepatide does not list blood clots as a side effect. This shows that the drug has a good safety record. There are some gastrointestinal issues and a few serious side effects reported. But there is no supported link between this drug and deep vein thrombosis or pulmonary embolism. 

It is important that health professionals and patients get information from official sources and look at clinical studies to know the true risks of this weight management drug. Medical records show no major concerns about blood coagulation when using this drug.

Clinical trials with tirzepatide weight loss have given us important insights about how safe and helpful it can be. The studies did not show a higher risk of blood clots, like deep vein thrombosis or pulmonary embolism, in people using this medicine. What they did find was that tirzepatide helps control blood sugar and supports weight loss. 

These are both key for people with cardiovascular disease. Doctors point out that it is important to watch for gastrointestinal side effects, but in general, they say tirzepatide is a good choice for those who want to improve their metabolic health.

How Does Tirzepatide Affect Cardiovascular Health?

Clinical trials on tirzepatide show some good news. The medicine does not harm the heart, and it may even help it a bit. These GLP-1 receptor agonists help the body make more insulin. They also lower how much you want to eat, and they help keep glucose levels in check. Altogether, this is good for cardiovascular disease and heart health.

In these trials, people had better blood flow and saw a drop in risk factors that are tied to cardiovascular disease. Most of the people in the study also saw weight management get better. This helps keep the strain off the heart that comes from a sedentary lifestyle. These details show the medicine could help many people have better heart health.

Can Weight Loss Medications Increase Blood Clot Risk?

Tirzepatide is a weight loss drug, but it is not known to be a big risk for blood clot formation. Some other drugs can change how blood coagulates. They may make the risk of deep vein thrombosis or pulmonary embolism go up. Tirzepatide works as a GLP-1 receptor agonist, and it does not naturally cause these serious health issues.

It is important to know that not all weight loss drugs act the same way or give the same side effects. Things such as a person’s deep vein problems, past health conditions, or other risks matter a lot when talking about blood clot issues and blood coagulation.

When you are thinking about weight management, it’s important to know how different medications work for weight loss. Medications like tirzepatide and semaglutide have different ways of helping you. 

They also have their own good points and risks. If you want to learn more about how these two affect blood sugar and what problems might come with them, you can check out the link below. Making informed choices is very important when it comes to your health, your blood sugar, and dealing with serious health issues.

Explore the comparison here: Tirzepatide vs. Semaglutide: Which Weight Loss Drug Works Best?

Is Compounded Tirzepatide Safe?

Healthon’s compounded tirzepatide gives people a good and steady way to lose weight when guided by a doctor. The team uses strong compounding rules to make sure every dose is safe and good quality. This care helps lower the risk of harmful side effects. 

Doctors also carefully check each person’s health conditions and their history of blood clots before they start. They make sure each person can use this medicine safely. This careful plan is there so patients stay safe and get good results. That is why compounded tirzepatide is a smart option for weight loss, weight management, and as part of diabetes medications.

If you want to know about the potential side effects of tirzepatide, including things like gastrointestinal issues or the risk of blood clot formation, you should check out the detailed article linked below. It is important to know about both the common and serious side effects before you start taking this medicine. 

The team at Healthon gives an easy breakdown of what you can expect when you begin taking tirzepatide. Your safety and comfort matter, so make sure you get the useful information shared there.
Learn more about tirzepatide side effects here.

We’re Here to Answer Any Questions

Questions around blood clots and Mounjaro have led to many people wanting answers. In this blog, you will learn about the possible risks, how tirzepatide may link to heart health, and if using different made formulations is safe. If you are trying to figure out any of these things, Healthon is here to support you at any time. If you have questions, our team can help you. You can contact us with your questions through our contact page. Find out more about safe weight management and blood sugar control today!

For people looking into treatment choices, Healthon has a simple plan for using tirzepatide. This medicine is known to help with weight management and blood sugar control. At Healthon, this treatment is given using strict safety rules. We always put patient screening first and follow all compounding standards. 

This helps us to make sure our compounded tirzepatide gives a good option for people who need help. If you want to know more or want to find out if this is the right way for you, visit our product page. There, you will get more details and guidance that is shaped for your health needs.

Frequently Asked Questions

Does Mounjaro cause blood clots in the legs or lungs?

While Mounjaro does not have a direct link to blood clots in the legs or lungs, people need to know that weight loss medications, including Mounjaro side effects, can have risks, including severe side effects. It is a good idea to talk to healthcare providers to get advice that fits your needs. Make sure to stay informed about the potential side effects of any medicine you use.

What are the official side effects of tirzepatide?

The known side effects of tirzepatide drugs are nausea, vomiting, diarrhea, constipation, and less hunger. There are also some bigger risks, including adverse effects such as pancreatitis and problems with how the kidneys work. Blood clots are not listed as a side effect in the FDA's current papers.

Should I stop taking Mounjaro if I’m worried about blood clots?

Talk to your healthcare provider if you have concerns about blood clots before you change anything with your Mounjaro routine. They will look at your health, think about the risks, and give you advice just for you, especially if there are product liability issues. If you have questions, consider contacting your doctor for a free consultation to help decide if stopping this medicine is best for you.

Is compounded tirzepatide safer than Mounjaro?

Compounded tirzepatide may be safer than Mounjaro if you take it with your doctor's care. Compounding rules help make sure that you get a mix made just for you that includes the active ingredient tirzepatide. However, you should also be aware of the statutes of limitations that may apply to your case. But, you should always talk with a healthcare professional first. Ask them about your health needs and any risks before using any medicine.

Reference List

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2. Robert King Law Firm. (n.d.). Mounjaro blood clots lawsuit. https://www.robertkinglawfirm.com/personal-injury/mounjaro-lawsuit/mounjaro-blood-clots-lawsuit/
   
   

3. Drugs.com. (2024). GLP-1 meds such as Ozempic, Mounjaro may lower clot risk in diabetes. https://www.drugs.com/news/glp-1-meds-such-ozempic-mounjaro-may-lower-clot-risk-diabetes-122762.html
   
   

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6. Healthon. (2025). Tirzepatide vs. Semaglutide: Which weight loss drug works best?
   
   

7. Healthon. (2025). Tirzepatide side effects: What you need to know before starting. https://www.healthon.com/blog/tirzepatide-side-effects-what-you-need-to-know-before-starting
   
   

8. National Institutes of Health. (n.d.). PubMed. https://pubmed.ncbi.nlm.nih.gov/
   
   

9. National Institutes of Health. (n.d.). PMC – U.S. National Library of Medicine. https://pmc.ncbi.nlm.nih.gov/
   
   

10. Centers for Disease Control and Prevention. (n.d.). Injection safety. https://www.cdc.gov/injectionsafety
    
    

11. Mayo Clinic. (n.d.). Mounjaro (tirzepatide) – Side effects and precautions. https://www.mayoclinic.org/drugs-supplements/tirzepatide-subcutaneous-route/description/drg-20534045
    
    

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13. American Heart Association. (n.d.). Cardiovascular disease and diabetes. https://www.heart.org
    
    

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15. Nature Medicine. (2024). Semaglutide cardiovascular outcomes. https://www.nature.com/articles/s41591-024-02996-7